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Autoimmune and immune-mediated skin disease
/content/chapter/10.22233/9781910443811.chap28
Autoimmune and immune-mediated skin disease
- Author: Hilary A. Jackson
- From: BSAVA Manual of Canine and Feline Dermatology
- Item: Chapter 28, pp 210 - 217
- DOI: 10.22233/9781910443811.28
- Copyright: © 2021 British Small Animal Veterinary Association
- Publication Date: September 2021
Abstract
This chapter covers the differential diagnosis and treatment for autoimmune and immune-mediated skin diseases, as well as the clinical approach to them.
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/content/chapter/10.22233/9781910443811.chap28
Figures
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28.1
(a) Symmetrical crusting on the haired skin and nasal planum of a dog with pemphigus foliaceus. (b) Multifocal crusts on the convex pinna of a dog with drug-induced pemphigus foliaceus.
(Courtesy of P Forsythe) © 2021 British Small Animal Veterinary Association
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28.1
(a) Symmetrical crusting on the haired skin and nasal planum of a dog with pemphigus foliaceus. (b) Multifocal crusts on the convex pinna of a dog with drug-induced pemphigus foliaceus.
(Courtesy of P Forsythe)
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28.2
Cytology of an intact pustule from a case of pemphigus foliaceus. Note the non-degenerate neutrophils and free-floating acantholytic keratinocytes. (Diff-Quik® stain; original magnification X1000) © 2021 British Small Animal Veterinary Association
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28.2
Cytology of an intact pustule from a case of pemphigus foliaceus. Note the non-degenerate neutrophils and free-floating acantholytic keratinocytes. (Diff-Quik® stain; original magnification X1000)
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28.3
Histology of pemphigus foliaceus. Note the intact subcorneal pustule. (H&E stain; original magnification X400) © 2021 British Small Animal Veterinary Association
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28.3
Histology of pemphigus foliaceus. Note the intact subcorneal pustule. (H&E stain; original magnification X400)
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28.4
Mucous membrane pemphigoid. Note the ulceration, crusting, cicatricial alopecia and loss of pigment. © 2021 British Small Animal Veterinary Association
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28.4
Mucous membrane pemphigoid. Note the ulceration, crusting, cicatricial alopecia and loss of pigment.
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28.5
Epidermolysis bullosa acquisita in a young Great Dane. Note the sloughing of the footpads. © 2021 British Small Animal Veterinary Association
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28.5
Epidermolysis bullosa acquisita in a young Great Dane. Note the sloughing of the footpads.
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28.6
Vesicular cutaneous lupus erythematosus in a Rough Collie. Note the polycyclic, serpigenous ulcerations on the ventral abdomen.
(Reproduced from
Jackson and Olivry (2001)
with permission from the publishers) © 2021 British Small Animal Veterinary Association
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28.6
Vesicular cutaneous lupus erythematosus in a Rough Collie. Note the polycyclic, serpigenous ulcerations on the ventral abdomen.
(Reproduced from
Jackson and Olivry (2001)
with permission from the publishers)
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28.8
(a, b) Ischaemic damage to the extremities (ear tips, nose and loss of tail) of a cat with idiopathic vasculitis. © 2021 British Small Animal Veterinary Association
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28.8
(a, b) Ischaemic damage to the extremities (ear tips, nose and loss of tail) of a cat with idiopathic vasculitis.
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28.9
Vascular infarct of the convex pinna caused by post-vaccination ischaemia. © 2021 British Small Animal Veterinary Association
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28.9
Vascular infarct of the convex pinna caused by post-vaccination ischaemia.
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28.10
Petechiae on the lateral flank associated with Rocky Mountain spotted fever (Rickettsia rickettsii). © 2021 British Small Animal Veterinary Association
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28.10
Petechiae on the lateral flank associated with Rocky Mountain spotted fever (Rickettsia rickettsii).
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28.11
Diascopy: with extravasation the lesions fail to blanche with pressure. © 2021 British Small Animal Veterinary Association
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28.11
Diascopy: with extravasation the lesions fail to blanche with pressure.
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28.12
Nasal arteritis in a St. Bernard. Note the ulceration confined to the nasal philtrum. © 2021 British Small Animal Veterinary Association
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28.12
Nasal arteritis in a St. Bernard. Note the ulceration confined to the nasal philtrum.
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28.13
Multifocal erosions associated with erythema multiforme. © 2021 British Small Animal Veterinary Association
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28.13
Multifocal erosions associated with erythema multiforme.
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28.14
Juvenile cellulitis in a 4-month-old Dachshund. (a) Crusting and draining tracts around the nose. (b) Swelling and serosanguineous exudate around the muzzle. Note the swelling around the neck due to lymphadenitis. © 2021 British Small Animal Veterinary Association
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28.14
Juvenile cellulitis in a 4-month-old Dachshund. (a) Crusting and draining tracts around the nose. (b) Swelling and serosanguineous exudate around the muzzle. Note the swelling around the neck due to lymphadenitis.