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Endocrine and multisystemic disease
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Endocrine and multisystemic disease
- Author: Lauren Powers
- From: BSAVA Manual of Guinea Pigs
- Item: Chapter 22, pp 264 - 274
- DOI: 10.22233/9781910443903.22
- Copyright: © 2026 British Small Animal Veterinary Association
- Publication Date: January 2026
Endocrine diseases are considered relatively uncommon in guinea pigs when compared with other mammalian species. However, there are several endocrine diseases of significant clinical importance in guinea pigs, most notably hyperthyroidism. This chapter covers diseases of the thyroid gland, parathyroid glands, adrenal glands, and endocrine and exocrine pancreas, as well as selected multisystemic, genetic and hepatobiliary diseases.
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Figures
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22.1
Positions of the major endocrine glands.
Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission. © 2026 British Small Animal Veterinary Association
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22.1
Positions of the major endocrine glands.
Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission.
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22.3
Weight loss and thin body condition in a 5-year-old entire boar with hyperthyroidism (top), compared with a healthy cagemate. © 2026 British Small Animal Veterinary Association
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22.3
Weight loss and thin body condition in a 5-year-old entire boar with hyperthyroidism (top), compared with a healthy cagemate.
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22.4
Visible thyroid mass along the ventral neck in a 5-year-old entire boar with hyperthyroidism. © 2026 British Small Animal Veterinary Association
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22.4
Visible thyroid mass along the ventral neck in a 5-year-old entire boar with hyperthyroidism.
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22.5
An adult entire sow with thyroid neoplasia involving the left thyroid lobe (arrowed) and an enlarged right submandibular lymph node affected by lymphoma (arrowhead). © 2026 British Small Animal Veterinary Association
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22.5
An adult entire sow with thyroid neoplasia involving the left thyroid lobe (arrowed) and an enlarged right submandibular lymph node affected by lymphoma (arrowhead).
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22.7
Ultrasonographic appearance of a bilobed thyroid mass in the 5-year-old entire boar with hyperthyroidism depicted in
Figure 22.3
. © 2026 British Small Animal Veterinary Association
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22.7
Ultrasonographic appearance of a bilobed thyroid mass in the 5-year-old entire boar with hyperthyroidism depicted in
Figure 22.3
.
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22.8
Right lateral radiograph showing an ossifying thyroid carcinoma in the 5-year-old entire boar with hyper-thyroidism depicted in
Figure 22.3
. The mass is visible radiographically along the ventral neck. © 2026 British Small Animal Veterinary Association
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22.8
Right lateral radiograph showing an ossifying thyroid carcinoma in the 5-year-old entire boar with hyper-thyroidism depicted in
Figure 22.3
. The mass is visible radiographically along the ventral neck.
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22.9
Surgical excision of a bilobed thyroid mass in the 5-year-old entire boar with hyperthyroidism depicted in
Figure 22.3
. © 2026 British Small Animal Veterinary Association
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22.9
Surgical excision of a bilobed thyroid mass in the 5-year-old entire boar with hyperthyroidism depicted in
Figure 22.3
.
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22.10
(a, b) Normal post-mortem appearance of the liver and gall bladder in the guinea pig. © 2026 British Small Animal Veterinary Association
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22.10
(a, b) Normal post-mortem appearance of the liver and gall bladder in the guinea pig.
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22.11
Hypovitaminosis C in a juvenile guinea pig. Note the (a) subcutaneous bruising and (b) haemorrhages at the costochondral junctions.
(Courtesy of MM Garner) © 2026 British Small Animal Veterinary Association
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22.11
Hypovitaminosis C in a juvenile guinea pig. Note the (a) subcutaneous bruising and (b) haemorrhages at the costochondral junctions.
(Courtesy of MM Garner)
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22.12
A hairless Skinny pig. © 2026 British Small Animal Veterinary Association
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22.12
A hairless Skinny pig.
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22.13
A guinea pig with lethal white syndrome. © 2026 British Small Animal Veterinary Association
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22.13
A guinea pig with lethal white syndrome.