Whenever a neurologist gives a talk to breeders or owners of dogs with epilepsy the topic of diet and cannabis comes up. Just as in real life! Can diet or cannabidiol influence antiepileptic drug response or even have antiepileptic properties? Medium chain triglyceride enriched diets have been shown to improve seizure control, cognition and fear response in dogs with idiopathic epilepsy. Furthermore, there is some evidence for a positive effect of cannabidiol, lifestyle changes and avoiding seizure triggers. “Every little helps” to get back control in canine epilepsy. This lecture addresses how to manage epilepsy more effectively and in synergy with conventional drug therapy.