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Continuous glucose monitoring systems

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Abstract

Continuous glucose monitoring systems (CGMSs) measure interstitial glucose. They offer a useful alternative to blood glucose monitoring. The newer systems, like the FreeStyle Libre®, are affordable, provide continuous data, and allow at-home monitoring. CGMSs sensors contain a platinum electrode and glucose oxidase membrane, generating a current proportional to interstitial glucose. Sensors typically last 5-14 days and correlate well with blood glucose levels. Proper placement on a stable, well-prepared skin surface (e.g., lateral thorax or neck) is essential. Owners need to activate sensors via the appropriate UK app.

When interpreting the output from a CGMS, at least three days of data collection is recommended before making any assessment of glycaemic control. These devices are less accurate in dehydrated or hypoglycemic animals and those experiencing rapid glucose fluctuations. This is due to a lag in equilibration of interstitial fluid and blood glucose and also changes in interstitial fluid composition. Studies show that CGMS improve owner experience, with 95% reporting better glycaemic control despite challenges with sensor fixation and cost. This session will discuss how to use and interpret a CGMS and the limitations of these systems using case examples as illustrations.

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