A drain is a conduit placed in the wound to remove fluid and air. This usually refers to surgical implants, typically Penrose drains or closed suction drains; however, an autogenous drain, the omentum, can be used in selective cases. An alternative method of providing wound drainage is to leave part of the wound open. This technique is effective in open peritoneal drainage and can also work well with severely contaminated or necrotic skin wounds. The chapter looks at Indications for drain usage; Types of drain; Drain placement; Postoperative and drain care; Drain removal; Complications; and Drains in specific surgeries. Case examples: Drainage of a flank abscess; Surgical management and drainage of a chronic mucocele. Operative techniques: Placement of a Penrose drain; Placement of an active suction drain