Despite the varied roles of ferrets, little specific pharmacological information is available for these animals. As small carnivores, ferrets share many pharmacological traits with the cat, such as a short gastrointestinal tract, rapid drug elimination and tolerance of similar antibiotics. Although they are similar to cats in some ways, they should not be treated as cats. Any extrapolation of drug dosages from cats or dogs to ferrets should be done cautiously, though for the most part drug dosages extrapolated from cats to ferrets are used with seemingly few disagreeable outcomes. This chapter observes Therapeutic approach; Routes and methods of medication; and Agents.