Tumours of the mammary glands

image of Tumours of the mammary glands
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Mammary tumours are the most common type of neoplasia in entire female dogs, representing approximately 50% of all tumours reported, although recently quoted to be as high as 70% of all cancer types. This chapter deals with canine mammary tumours; feline mammary tumours.

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16.3 Histological specimen showing skin infiltration and neoplastic thrombi and skin ulceration in an anaplastic carcinoma. (Original magnification X100) (Courtesy of Dr Arman Shokrai, National Veterinary Institute, Uppsala, Sweden)
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16.5 Osteosarcoma in an 8-year-old intact female Bichon Havanais.
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16.6 Cytological specimen from a dog with tubulopapillary adenocarcinoma. Cytology is rarely helpful in confirming degree of malignancy or type in canine mammary gland tumours, but inflammation, hyperplasia and non-mammary gland malignancies can often be differentiated. As with other carcinomas, features of malignancy include anisokaryosis, anisocytosis, increased basophilia, cellular piling, and large prominent and/or multiple nucleoli. Sometimes acinar structures can be seen. (Original magnification X100)
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16.7 Multiple metastases in the lungs of a dog with adenocarcinoma simplex. (Courtesy of the Division of Diagnostic Imaging, University Small Animal Hospital, Uppsala, Sweden)
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16.8 Skeletal metastasis is much more frequent in humans with breast cancer than in canine mammary tumours. This scintigraphy examination revealed a rib metastasis in a dog with a highly aggressive anaplastic carcinoma. (Courtesy of the Division of Diagnostic Imaging, University Small Animal Hospital, Uppsala, Sweden)
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16.9 An approach to management of canine and feline mammary tumours.
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16.11 Mammary fibroadenomatous hyperplasia in a 4-year-old DSH queen (after progestin treatment). Multiple hyperplastic glands are bilaterally significantly enlarged, with oedema and ulceration of the skin in the first two cranial glands. Macroscopically, the tumour is multinodular and light yellow. Histopathology shows a netlike pattern building up epithelial ducts. (H&E, orginal magnification X100) (b,c courtesy of Erika Karlstam, National Veterinary Institute, Uppsala, Sweden)
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