Principles of chemotherapy

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Chemotherapy is a common treatment modality in veterinary cancer medicine. This chapter looks at general principles and considerations; drugs; new frontiers.

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7.8 Equipment used to minimize occupational exposure to chemotherapy agents. Biological safety cabinet. Chemotherapy pin used to prevent aerosolization of any drug.
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7.9 PhaSeal system components: protective cap, which is fixed to the pharmaceutical bottle; injector Luer, which consists of an encapsulated specially ground cannula, used in both preparation and administration. Administration to the patient.
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7.13 Most cytotoxic drugs are administered via a cleanly placed intravenous catheter. Small volumes of drug given as a bolus can be given through a butterfly catheter. This dog is receiving vincristine into a lateral saphenous vein.
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7.17 Alopecia in a poodle following treatment with doxorubicin. Alopecia, including whisker loss, in a cat with lymphoma treated with cyclophosphamide and vincristine. The cat’s hair regrew after discontinuation of treatment.
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7.19 A tissue reaction following vincristine extravasation and the healed area several months later.
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7.20 Hypersensitivity reaction during doxorubicin administration in a Bloodhound. Note the oedema around the eyes and swelling, redness and induration of the lips.
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