1887

Structure and function of the skin

image of Structure and function of the skin
GBP
Online Access: GBP25.00 + VAT
BSAVA Library Pass Buy a pass

Abstract

The skin is the largest of the organs. It performs a wide variety of functions vital to maintenance of the homeostatic status of the body and plays an active role in immune responses via the innate and acquired immune system. In addition, different regions of the skin such as the ears, eyelids, lips, prepuce, footpads and claws have specialized functions and differ structurally from the skin that covers the general body surface. A consideration of all these topics is beyond the scope of this chapter. Attention will be concentrated on the anatomy and physiology of the unspecialized skin and its role in body defence, with the aim of providing a basis for understanding the pathogenesis of cutaneous disease. The chapter focuses on the epidermis; hair and its associated structures; the dermoepidermal junction; the dermis, and the skin as an immune organ.

Loading full text...

Full text loading...

/content/chapter/10.22233/9781905319886.chap1

Figures

Image of 1.2
1.2 Epidermis showing the organization of the cells and their maturation into fully cornified cells. © Anita Patel.
Image of 1.4
1.4 Scanning electron mircrograph of frozen hydrated canine stratum corneum, showing the compact layered arrangement of the squames. (Courtesy of IS Mason and DH Lloyd)
Image of 1.5
1.5 Frozen section of bovine skin after treatment with an alkaline buffer, swelling the stratum corneum. Red-staining lipid (Sudan IV stain) can be seen in the distal intercellular layers of the corneum. The stratum corneum is somewhat thinner in dogs and cats. LE = living epidermis; SC = stratum corneum.
Image of 1.6
1.6 The hair growth cycle. Anagen, the active growth phase, is divided into six stages: proanagen, stages I–IV; mesanagen, stage V; and metanagen, stage VI. During these stages the hair follicle undergoes differentiation, rapid growth and hair elongation. Telogen represents the resting phase of the hair follicle, and catagen is the transitional period between the growth and resting phases. © Anita Patel.
Image of 1.8
1.8 The hair follicle and its associated structures. © Anita Patel.
Image of 1.10
1.10 Scanning electron micrograph of a normal canine hair. The surface is tiled with cells of the cuticle, which point away from the base of the hair.
Image of 1.12
1.12 Components of mammalian skin, including epidermal structures (compound hair follicle and adnexal structures, free sebaceous gland, atrichial sweat gland), blood supply, nerves and associated mechanoreceptors. © Anita Patel.
Image of 1.13
1.13 Structural components of the dermoepidermal junction. © Anita Patel.
Image of 1.14
1.14 Section through canine skin, illustrating the dermal connective tissue structure. The deep dermis is characterized by thicker and denser collagen (silver stain). High-power view showing elastin fibres surrounding a hair follicle. (Gomori’s aldehyde fuchsin with light green stain: collagen = green; elastin fibres = mauve.)
Image of 1.15
1.15 A section of bovine skin stained with haematoxylin following arterial perfusion with Indian ink. Note that the thin, superficial epidermal tissue is avascular.

More like this

/content/chapter/10.22233/9781905319886.chap1
dcterms_title,dcterms_description
-contentType:Journal
5
5
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error