Staff are likely to be the practice’s biggest ongoing expense. For most practices somewhere in the region of 40% of outgoing costs will be spent of staff salaries and recruitment. However, staff are also the practice’s greatest asset. They are the face of the practice and generate the practice’s income. This chapter looks at staffing the practice; organizational structures; equal opportunities; the practice manual and staff handbook; recruitment; shared values; empowering staff; staff motivation; teams and teamwork; staff training and development; and how to handle grievances and disciplinary issues.