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Laboratory evaluation of renal disorders

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Abstract

The function of the kidneys is to regulate the volume and composition of extracellular fluid. This is achieved by the initial formation of an ultrafiltrate of plasma by the passage of solutes, small proteins and other non-scellular constituents of the blood across the glomerular filtration barrier. The chapter deals with glomerular filtration, laboratory abnormalities in patients with kidney disease, staging chronic kidney disease, acute kidney injury, glomerular barrier function and tubular function. This chapter includes case examples.

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Figures

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11.3 Relationship between creatinine concentration and glomerular filtration rate (GFR). Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission.
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11.8 Inter-relation of parathyroid hormone (PTH), fibroblast growth factor (FGF)-23 and 1,25(OH) -vitamin D in CKD. iCa = ionized calcium. Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission.
Image of 11.12
11.12 Suggested flow chart for the work-up of dogs and cats with protein-losing nephropathy (PLN). FeLV = feline leukaemia virus; PE = physical examination; PLI = pancreatic lipase immunoreactivity; SCWT = Soft Coated Wheaten Terrier; UTI = urinary tract infection. Drawn by S.J. Elmhurst BA Hons (www.livingart.org.uk) and reproduced with her permission.

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