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Management of chronic kidney disease

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Abstract

For patients that develop chronic kidney disease, the underlying aetiology may never be identified. Irrespective of the inciting injury, the histopathological response to injury in the kidneys is the same, and tubulo-interstitial nephritis and fibrosis with variable degrees of secondary glomerulosclerosis and mineralization are usually identified. This chapter concerns itself with factors associated with progression of CKD, and treatment and management strategies for patients with CKD.

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Figures

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23.2 Regulation of phosphorus in feline and canine patients with chronic kidney disease (CKD). IRIS = International Renal Interest Society.
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23.4 The use of daily calcitriol therapy in dogs with IRIS CKD Stages 3 and 4. CKD = chronic kidney disease; IRIS = International Renal Interest Society; PTH = parathyroid hormone.
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23.5 Management of proteinuria in dogs and cats with confirmed IRIS CKD Stages 1 to 3. ACEi = angiotensin-converting enzyme inhibitor; ARB = angiotensin receptor blocker; RAAS = renin–angiotensin–aldosterone system; SBP = systolic blood pressure; UPC = urine protein to creatinine ratio.
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23.8 Flow diagram for the administration of darbepoetin in cats or dogs with chronic kidney disease. CBC = complete blood count; CKD = chronic kidney disease; PCV = packed cell volume; TP= total protein.

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