Anaemia of chronic renal disease

image of Anaemia of chronic renal disease
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Anaemia is a common problem in cats and dogs with chronic renal disease. The signs and symptoms of anaemia in patients with chronic renal disease do not differ from those seen in other patients with chronic anaemia, and include pallor of the mucous membranes and skin, tachycardia, tachypnoea, lethargy, weakness and anorexia. The chapter looks at pathophysiology; clinical evaluation; treatment; future directions.

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10.1 Synthesis and regulation of erythropoietin.
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10.2 Serum erythropoietin (EPO) concentrations in healthy and anaemic dogs compared with dogs with anaemia of chronic renal failure.
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10.4 Response to treatment with darbepoetin in a 13-year-old cat with anaemia of chronic renal failure. The PCV increased to about 25% in response to weekly injections. The frequency of treatment with darbepoetin (arrows) was lowered at that time so that it was given every 2–4 weeks.
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