Non-regenerative anaemia

image of Non-regenerative anaemia
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Non-regenerative anaemias result from reduced or ineffective erythropoiesis; however, identification of a specific underlying cause is important, because the prognosis and treatment will depend on the underlying pathogenesis. This chapter covers aplastic anaemia; pure red cell aplasia; myelofibrosis; myelodysplastic syndromes; neoplasia/leukaemia.

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9.1 Histological section of bone marrow from a dog with aplastic anaemia. The few cells remaining are primarily small lymphocytes.
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9.2 Bone marrow aspirate from a dog showing macrophages containing organisms (arrows). Bar, 20 μm.
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9.4 Histological section of bone marrow from a dog showing haemorrhage (small arrow), oedema and fibrin deposition (large arrows), and an increase in plasma cells (arrowheads).
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9.5 Histological section of bone marrow from a dog showing an area of fibrosis (large arrows) and an acute inflammatory infiltrate (small arrows).
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