1887

Disorders of secondary haemostasis

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Abstract

Inherited disorders of secondary haemostasis are usually deficiencies of single clotting factors that arise as a result of genetic mutations, although deficiencies in multiple factors may occur. Acquired disorders of coagulation are generally deficiencies of multiple factors and may occur in conjunction with platelet disorders. This chapter considers clinical approach to coagulopathies; inherited coagulopathies; acquired coagulopathies.

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Figures

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25.1 Lameness caused by bleeding into the stifle joint in a 6-month-old St Bernard with severe haemophilia B.
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25.2 Massive bleeding during shedding of teeth in a St Bernard with severe haemophilia B (same patient as Figure 25.1 ).
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25.3 Haemorrhage following neutering in a male Rhodesian Ridgeback with haemophilia B.
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25.4 Radiograph illustrating compression of the trachea by a massive haematoma in the neck of a Dachshund with anticoagulant rodenticide intoxication.
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25.5 Factor IX activity in a dog with haemophilia B during repeated treatment with 20 ml/kg fresh frozen plasma (arrows). (Source: )
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25.7 Vitamin K-dependent coagulopathy of Devon Rex cats: perineal bruising and scrotal haematoma in an affected male cat after surgery. (Courtesy of Steve Shaw)

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