Clinical pathology

image of Clinical pathology
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This chapter addresses haematology, blood biochemistry, urinalysis, cerebrospinal fluid, serology, bone marrow and cytology in relation to rabbits.

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9.2 Erythrocyte polychromasia and anisocytosis are a normal finding on rabbit blood smears.
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9.3 A small lymphocyte.
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9.4 A heterophil; note the rod-shaped granules.
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9.5 An eosinophil; note the more prominent rounded granules.
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9.6 A monocyte.
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9.7 Basophil (B) and heterophil (H); also present are platelet clumps.
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9.14 Fine-needle aspirate from a case of steatitis in the dewlap of a rabbit. There are abundant erythrocytes, with a few macrophages and a few heterophils. As there is no fat on this smear, a diagnosis of steatitis would not be possible from it alone, only chronic active inflammation. (May–Grünwald Giemsa; original magnification X400) © Chris Knott.
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9.15 Fine-needle aspirate from a cutaneous mass. Apart from erythrocytes (probably contamination during sampling) it consists largely of keratin squames (nucleated and non-nucleated) and clumps of keratinous debris. This is typical of a keratinizing cystic lesion such as an epidermal cyst, infundibular keratinizing acanthoma, or one of the various benign skin adnexal tumours such as trichofolliculoma, trichoepithelioma or pilomatrixoma. (May–Grünwald Giemsa; original magnification X200) © Chris Knott.
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9.16 Fine-needle aspirate from a subcutaneous cystic swelling. There are abundant moderately cohesive cells, which look at first sight somewhat like adipocytes from a lipoma, but they are smaller. These are very suggestive of mesenchymal stellate cells from the larval cestode in a coenurus cyst (probably ). (May–Grünwald Giemsa; original magnification X200) Histology of the lesion, which was removed a few days after aspiration, shows multiple larval cestodes within the coenurus. Note the hooklets on the protoscolex and the abundant parenchymal stellate cells. (H&E; original magnification X100) © Chris Knott.
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9.17 The typical appearance of a fine-needle aspirate from a lipoma, showing a sheet of ruptured and collapsed adipocytes. This aspirate contains a few intact adipocytes. (May–Grünwald Giemsa; original magnification X400) © Chris Knott.

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