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Disseminated intravascular coagulation
/content/chapter/10.22233/9781905319732.chap30
Disseminated intravascular coagulation
- Authors: Bo Wiinberg and Annemarie T. Kristensen
- From: BSAVA Manual of Canine and Feline Haematology and Transfusion Medicine
- Item: Chapter 30, pp 264 - 271
- DOI: 10.22233/9781905319732.30
- Copyright: © 2012 British Small Animal Veterinary Association
- Publication Date: January 2012
Abstract
Disseminated intravascular coagulation (DIC) is a complicated and dynamic haemostatic syndrome characterized by simultaneous variable imbalances of several components of the haemostatic system. This chapter covers aetiology of DIC; pathophysiology; biomarkers; diagnosis; treatment.
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Figures
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30.1
Pathophysiology of disseminated intravascular coagulation (DIC) as proposed by
Bick (2003)
. AT, antithrombin; FDPs, fibrin degradation products; PC, protein C; PS, protein S; TF, tissue factor; TFPI, tissue factor pathway inhibitor; TNF-α, tumour necrosis factor-α. © 2012 British Small Animal Veterinary Association
10.22233/9781905319732/fig30_1_thumb.gif
10.22233/9781905319732/fig30_1.png
30.1
Pathophysiology of disseminated intravascular coagulation (DIC) as proposed by
Bick (2003)
. AT, antithrombin; FDPs, fibrin degradation products; PC, protein C; PS, protein S; TF, tissue factor; TFPI, tissue factor pathway inhibitor; TNF-α, tumour necrosis factor-α.
/content/figure/10.22233/9781905319732.chap30.ch30fig3
30.3
Diagnostic and therapeutic decision tree for patients with disseminated intravascular coagulation (DIC). aPTT, activated partial thromboplastin time; AT, antithrombin; CBC, complete blood count; FDP, fibrin degradation products; PT, prothrombin time; TEG, thromboelastography. a Controversial treatment. © 2012 British Small Animal Veterinary Association
10.22233/9781905319732/fig30_3_thumb.gif
10.22233/9781905319732/fig30_3.png
30.3
Diagnostic and therapeutic decision tree for patients with disseminated intravascular coagulation (DIC). aPTT, activated partial thromboplastin time; AT, antithrombin; CBC, complete blood count; FDP, fibrin degradation products; PT, prothrombin time; TEG, thromboelastography. a Controversial treatment.