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Hypoparathyroidism

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Abstract

This chapters focuses on hypoparathyroidism, an uncommon disease that can affect both dogs and, rarely, cats. In dogs the disease is most frequently an idiopathic primary hypoparathyroidism that results from immune-mediated destruction of the parathyroid glands. Hypoparathyroidism is characterized by low circulating ionized and total calcium concentrations in combination with a low parathyroid hormone concentration and an elevated phosphate concentration.

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Figures

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7.1 Calcium homeostasis: the role of parathyroid hormone (PTH) and 1,25-(OH)-vitamin D in the maintenance of adequate serum calcium.
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7.3 Ocular changes in dogs with hypoparathyroidism. This lens in a Border Collie shows marked linear opacities in the anterior and posterior subcapsular cortex as well as anterior and posterior suture lines. Visual acuity would be expected to be affected, although the dog was still able to negotiate obstacles. (Courtesy of David Williams) Punctate opacities in a lens from a different case. (Courtesy of David Gould)
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7.5 Dramatic skin sloughing in a Border Collie that had received subcutaneous calcium gluconate in several sites. (Courtesy of Andria Cauvin)

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