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  3. Acetylcysteine
Acetylcysteine
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Acetylcysteine

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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition. 
  1. Aldavood SJ, Behyar R, Sarchahi AA et al. (2003) Effect of acetylcysteine on experimental corneal wounds in dogs. Ophthalmic Research 35 , 319–323
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  2. Aronson LR and Drobatz K (1996) Acetaminophen toxicosis in 17 cats. Journal of Veterinary Emergency and Critical Care 6, 65–69
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  3. Buur JL, Diniz P, Roderick K, Kukanich B and Tegzes J (2013) Pharmacokinetics of N-acetylcysteine after oral and intravenous administration to healthy cats. American Journal of Veterinary Research 74, 290–293
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  4. Dunayer EK (2006) New Findings on the effects of xylitol ingestion in dogs. Veterinary Medicine 101 , 791–796
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  5. El Bahri L and Lariviere N (2003) N-Acetylcysteine. Compendium of Continuing Education for Veterinarians 25, 276–278
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  6. Gaykwad C, Garkhal J, Chethan GE et al. (2018) Amelioration of oxidative stress using N-acetylcysteine in canine parvoviral enteritis. Journal of Veterinary Pharmacology and Therapeutics 41, 68–75
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  7. Kimmitt BA, Moore GE and Stiles J (2018) Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model. American Journal Veterinary Research 79, 555–561
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  8. May ER, Ratliff BE and Bemis DA (2019) Antibacterial effect of N-acetylcysteine in combination with antimicrobials on common canine otitis externa bacterial isolates. Veterinary dermatology 30, 531–e161
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  9. Ortillés Á, Leiva M, Allgoewer I and Peña MT (2020) Intracanalicular injection of N-acetylcysteine as adjunctive treatment for sialoceles in dogs: 25 cases (2000–2017). Journal of the American Veterinary Medical Association 257, 826–832
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  10. Reinero CR, Lee-Fowler TM, Dodam JR et al. (2011) Endotracheal nebulization of N-acetylcysteine increases airway resistance in cats with experimental asthma. Journal of Feline Medicine and Surgery 13, 69–73
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  11. Richardson JA (2000) Management of acetaminophen and ibuprofen toxicoses in dogs and cats. Journal of Veterinary Emergency and Critical Care 10 , 285–291
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  12. Savides MC, Oehme FW and Leipold HW (1985) Effects of various antidotal treatments on acetaminophen toxicosis and biotransformation in cats. American Journal of Veterinary Research 46, 1485–1489
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  13. St Omer VE and Mohammad FK (1984) Effect of antidotal N-acetylcysteine on the pharmacokinetics of acetaminophen in dogs. Journal of Veterinary Pharmacology and Therapeutics 7, 277–281
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  14. Villar D, Buck WB and Gonzalez JM (1998) Ibuprofen, aspirin and acetaminophen toxicosis and treatment in dogs and cats.Veterinary and Human Toxicology 40, 156–162
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