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  3. Ciclosporin (Cyclosporin(e))
Ciclosporin (Cyclosporin(e))
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Ciclosporin (Cyclosporin(e))

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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition. 
  1. Nuttall T ,Reece D andRoberts E (2014)Life-long diseases need life-long treatment: long-term safety of ciclosporin in canine atopic dermatitis. Veterinary Record 174 ,3–12
  2. Swann JW, Garden OA, Fellman CL et al.(2019) ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. Journal of Veterinary Internal Medicine  29, 513–518
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  3. Allenspach K, Refenacht S, Sauter S et al. (2006) Pharmacokinetics and clinical efficacy of cyclosporine treatment of dogs with steroid-refractory inflammatory bowel disease.Journal of Veterinary Internal Medicine20, 239–44
  4. Bexfield NH, Watson PJ and Herrtage ME (2006) Management of myasthenia gravis using cyclosporine in 2 dogs.Journal of Veterinary Internal Medicine20, 1487–1490
  5. Dreyfus J, Schobert CS and Dubielzig RR (2011) Superficial corneal squamous cell carcinoma occurring in dogs with chronic keratitis.Veterinary Ophthalmology14, 161–168
  6. Gilger BC, Andrews J, Wilkie DA and Lairmore MD (1996) Lymphocyte proliferation and blood drug levels in dogs with keratoconjunctivitis sicca receiving long-term topical ocular cyclosporine.Veterinary Comparative Ophthalmology6, 125–130
  7. House AK, Guitian J, Gregory SP and Hardie RJ (2006) Evaluation of the effect of two dose rates of cyclosporine on the severity of perianal fistulae lesions and associated clinical signs in dogs.Veterinary Surgery35, 543–549
  8. Kaswan RL and Salisbury MA (1990) A new perspective on canine keratoconjunctivitis sicca: treatment with ophthalmic cyclosporine.Veterinary Clinics of North America: Small Animal Practice20, 583–613
  9. Linek M, Boss C, Haemmerling R, Hewicker-Trautwein M and Mecklenburg L (2005) Effects of cyclosporine A on clinical and histologic abnormalities in dogs with sebaceous adenitis.Journal of the American Veterinary Medical Association226, 59–64
  10. Morgan RV and Abrams KL (1991) Topical administration of cyclosporine for treatment of keratoconjunctivitis sicca in dogs.Journal of the American Veterinary Medical Association199, 1043–1046
  11. Pierce KE Jr, Wilkie DA, Gemensky-Metzler AJ et al. (2016) An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats.Veterinary Ophthalmology S1, 77–85
  12. Roberts ES ,Tapp T ,Trimmer A et al. (2016)Clinical efficacy and safety following dose tapering of ciclosporin in cats with hypersensitivity dermatitis. Journal of Feline Medicine and Surgery 18 ,898–905
  13. Sansom J, Barnett KC, Neumann W et al. (1995) Treatment of keratoconunctivitis sicca in dogs with cyclosporine ophthalmic ointment: European clinical field trial.Veterinary Record137, 504–507
  14. Williams DL (2010) Lack of effects on lymphocyte function from chronic topical ocular cyclosporine medication: a prospective study.Veterinary Ophthalmology13, 315–320
  15. Williams DL, Hoey AJ and Smitherman P (1995) Comparison of topical cyclosporine and dexamethasone for the treatment of chronic superficial keratitis in dogs.Veterinary Record137, 635–639
  16. Spiess AK, Sapienza JS and Mayordomo A (2009) Treatment of proliferative feline eosinophilic keratitis with topical 1.5% cyclosporine: 35 cases. V eterinary Ophthalmology 12, 132–137
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