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  2. BSAVA Small Animal Formulary Part A: Canine and Feline
  3. Cytarabine (Cytosine arabinoside, Ara-C)
Cytarabine (Cytosine arabinoside, Ara-C)
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Cytarabine (Cytosine arabinoside, Ara-C)

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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition. 
  1. Alvarez FJ, Kisseberth WC, Gallant SL and Couto CG (2006) Dexamethasone, melphalan, actinomycin D, cytosine arabinoside (DMAC) protocol for dogs with relapsed lymphoma. Journal of Veterinary Internal Medicine 20, 1178–1183
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  2. Gunther Ch, Steffen F, Alder DS et al. (2020) Evaluating the use of cytosine arabinoside for treatment of recurrent canine steroid responsive meningitis arteritis. The Veterinary Recod 187, e7
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  3. Guillen A, Finotello R, Wynne P et al. (2020) Toxicity of cytarabine constant rate infusion in dogs with high-grade non-Hodkin lymphoma with bone marrow or central nervous system involvement. Australian Veterinary Journal 98, 69–78
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  4. Hart SK and Waddel L (2016) Suspected drug-induced infiltrative lung disease culminating in acute respiratory failure in a dog treated with cytarabine and prednisolone. Journal of Veterinary Emergency and Critical Care (San Antonio) 26, 844–850
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  5. Lowrie M, Thomson S, Smith P and Garosi L (2016) Effect of a constant rate infusion of cytosine arabinoside on mortality in dogs with meningoencephalitis of unknown origin. The Veterinary Journal 213, 1–5
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  6. Mancini SL, Early PJ, Slater BM et al. (2022) Novel subcutaneous cytarabine infusion with the Omnipod system in dogs with meningoencephalomyelitis of unknown etiology. American Journal of Veterinary Research 83, DOI: 10.2460/ajvr.22.03.0046
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  7. Marconato L, Bonfanti U, Stefanello D et al. (2008) Cytosine arabinoside in addition to VCAA‐based protocols for the treatment of canine lymphoma with bone marrow involvement: does it make the difference? Veterinary Comparative Oncology 6, 80–89
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  8. Ruslander D, Moore AS, Gliatto JM et al. (1994) Cytosine arabinoside as a single agent for the induction of remission in canine lymphoma. Journal of Veterinary Internal Medicine 8 , 299–301
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  9. Smallwood K, Harper A and Blackwood L (2021) Lomustine, methotrexate and cytarabine chemotherapy as a rescue treatment for feline lymphoma. Journal of Feline Medicine and Surgery 23, 722–729
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  10. Volk AV, Volk HA, Rest JR et al. (2012) Calcinosis cutis at cytarabine injection site in three dogs receiving prednisolone. The Veterinary Record 171, 327
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  11. Zarfoss M, Schatzberg S, Venator K et al. (2006) Combined cytosine arabinoside and prednisone therapy for meningoencephalitis of unknown aetiology in 10 dogs. Journal of Small Animal Practice 47 , 588–595
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