1887

Imepitoin

This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition
  1. Charalambous M, Muñana K, Patterson EE et al. (2024) ACVIM Consensus Statement on the management of statusepilepticus and cluster seizures in dogs and cats. Journal of Veterinary Internal Medicine 38, 19–40
  2. Engel O, Masic A, Landsberg G et al. (2018) Imepitoin shows benzodiazepine-like effects in models of anxiety. Frontiers in Pharmacology 9, 1225
  3. Engel O, Müller HW, Klee R, Francke B and Mills DS (2019) Effectiveness of imepitoin for the control of anxiety and fear associated with noise phobia in dogs. Journal of Veterinary Internal Medicine 33, 2675–2684
  4. Engel O, von Klopmann T, Maiolini A et al. (2017) Imepitoin is well tolerated in healthy and epileptic cats. BMC Veterinary Research 13, 172
  5. Forster B, Engel O, Erhard M and Bartels A (2020) Short-term imepitoin treatment reduces stress level in dogs with generalized anxiety disorder. Journal of Veterinary Behavior 38, 67–73
  6. Gallucci A, Gagliardo T, Menchetti M et al. (2015) Efficacy of imepitoin as first choice drug in treatment of 53 naïve dogs affected by idiopathic epilepsy. In: Proceedings of the 28th Symposium ESVN-ECVN. Journal of Veterinary Internal Medicine 30, 446
  7. McPeake KJ and Mills DS (2017) The use of imepitoin (Pexion™) on fear and anxiety related problems in dogs – a case series. BMC Veterinary Research 13, 173
  8. Muñoz Amezcua AC, Jones JM, Griffith EH and Gruen ME (2024) Pilot study on the efficacy and safety of long-term oral imepitoin treatment for control of (thunder) storm-associated noise phobia/noise aversion in dogs using an individualized-dose titration approach. Animals 14, 545
  9. Perdew I, Emke C, Johnson B et al. (2021) Evaluation of Pexion®(imepitoin) for treatment of storm anxiety in dogs: A randomised, double‐blind, placebo‐controlled trial. Veterinary Record 188, e18
  10. Royaux E, Bhatti S, De Cock H et al. (2016) Cutaneous adverse drug reaction in a dog associated with imepitoin. Veterinary Dermatology 27, 118–121
  11. Rundfeldt C, Tipold A and Löscher W (2015) Efficacy, safety, and tolerability of imepitoin in dogs with newly diagnosed epilepsy in a randomized controlled clinical study with long-term follow up. BMC Veterinary Research 11, 228
  12. Stabile F, van Dijk J, Barnett CR and De Risio L (2019) Epileptic seizure frequency and semiology in dogs with idiopathic epilepsy after initiation of imepitoin or phenobarbital monotherapy. The Veterinary Journal 249, 53–57
  13. Tipold A, Keefe TJ, Löscher W et al. (2015) Clinical efficacy and safety of imepitoin in comparison with phenobarbital for the control of idiopathic epilepsy in dogs. Journal of Veterinary Pharmacology and Therapeutics 38, 160–168
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error