1887

Leflunomide

This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition
  1. Affolter VK and Moore PF (2000) Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells. American Journal of Dermatopathology 22, 40–48
  2. Chesne RB, Doornink MT, Sri-Jayantha LSH and Urie BK (2024) Leflunomide with prednisone or nonsteroidal anti-inflammatory drug therapy is safe and tolerated for long-term treatment of immune-mediated polyarthritis in 27 dogs. Journal of the American Veterinary Medical Association 262, 1188–1192
  3. Colopy SA, Baker TA and Muir P (2010) Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006–2008). Journal of the American Veterinary Medical Association 236, 312–318
  4. Gregory CR, Stewart A, Sturges B et al. (1998) Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy. Transplant Proceedings 30, 4143–4148
  5. Mehl ML, Tell L, Kyles AE et al. (2012) Pharmacokinetics and pharmacodynamics of A77 1726 and leflunomide in domestic cats. Journal of Veterinary Pharmacology and Therapeutics 35, 139–146
  6. Sato M, Veir JK, Legare M and Lappin MR (2017) A retrospective study on the safety and efficacy of leflunomide in dogs. Journal of Veterinary Internal Medicine 31,1502–1507
  7. Wilson R, Swift I, Groth-Semple M et al. (2024) Treatment with leflunomide in conjunction with glucocorticoids for dogs with immune-mediated polyarthritis is not associated with improved outcomes: A retrospective cohort study of 93 dogs from Australia (2017-2024). Veterinary Sciences 11, 537
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