Loperamide
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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition.
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Cartagena-Albertus JC, Manchado JE, Moise A, García SM and Alonso JAM (2019) Assessment of the administration of maropitant and loperamide to dogs with cancer for the prevention and reduction of adverse effects associated with the administration of paclitaxel.American Journal of Veterinary Research 80, 601 – 606
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Fioramonti J, Fargeas M-J and Bueno L (1987) Stimulation of gastrointestinal motility by loperamide in dogs.Digestive Diseases and Sciences 32, 641 – 646
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Hugent C, Cadore JL, Buronfosse F et al.(1996) Loperamide poisoning in the dog.Veterinary and Human Toxicology 38, 31 – 33
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Long WM, Sinnott VB, Bracker K and Thomas D (2017) Use of 20% intravenous lipid emulsion for the treatment of loperamide toxicosis in a Collie homozygous for the ABCB1-1∆ mutation.Journal of Veterinary Emergency and Critical Care 27, 357 – 361
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Mackerer CR, Clay GA and Dajani EZ (1976) Loperamide binding to opiate receptors of brain and myenteric plexus.Journal of Pharmacology and Experimental Therapeutics 199, 131 – 140
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Myers MJ, Martinez M, Li H et al.(2015) Influence of ABCB1 genotype in Collies on the pharmacokinetics and pharmacodynamics of loperamide in a dose-escalation study.Drug Metabolism and Disposition 43, 1392 – 1407
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Sartor LL ,Bentjen SA ,Trepanier L et al.(2004)Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity. Journal of Veterinary Internal Medicine 18 ,117–118