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  3. Omeprazole
Omeprazole
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Omeprazole

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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition. 
  1. Jones SM, Gaier A, Enomoto H et al. (2020) The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs.Journal of Veterinary Internal Medicine 34, 1886–1893
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  2. Shaevitz MH, Moore GE and Fulkerson CM (2021) A prospective, randomized, placebo-controlled, double-blinded clinical trial comparing the incidence and severity of gastrointestinal adverse events in dogs with cancer treated with piroxicam alone or in combination with omeprazole or famotidine.Journal of the American Veterinary Medical Association 259, 385–391
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  3. Bersenas AM, Mathews KA, Allen DG and Conlon PD (2005) Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs.American Journal of Veterinary Research 66, 425–431
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  4. Brooks D and Watson GL (1997) Omeprazole in a dog with gastrinoma.Journal of Veterinary Internal Medicine 11, 379 – 381
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  5. Davis MS, Willard MD, Nelson SL et al.(2003) Efficacy of omeprazole for the prevention of exercise-induced gastritis in racing Alaskan sled dogs. Journal of Veterinary Internal Medicine  17, 163–166
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  6. Gaier A, Price J, Grubb L, Fitzgerald S and Tolbert MK (2021) A prospective, randomized, masked, placebo-controlled crossover study for the effect of 10 mg omeprazole capsules on gastric pH in healthy dogs.Journal of Veterinary Internal Medicine 35, 887 – 891
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  7. Garcia-Mazcorro JF, Suchodolski JS, Jones KR et al. (2012) Effect of the proton pump inhibitor omeprazole on the gastrointestinal bacterial microbiota of healthy dogs.FEMS Microbiology and Ecology 80, 624–636
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  8. Garcia RS, Belafsky PC, Della Maggiore A et al. (2017) Prevalence of Gastroesophageal Reflux in Cats During Anesthesia and Effect of Omeprazole on Gastric pH. Journal of Veterinary Internal Medicine  31, 734–742
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  9. Hwang JH, Jeong JW, Song GH et al.(2017) Pharmacokinetics and acid suppressant efficacy of esomeprazole after intravenous, oral, and subcutaneous administration to healthy Beagle dogs. Journal of Veterinary Internal Medicine  31, 743–750
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  10. Kuhl A, Odunayo A, Price J et al. (2020) Comparative analysis of the effect of IV administered acid suppressants on gastric pH in dogs. Journal of Veterinary Internal Medicine 34, 678–683
  11. Lotti F, Twedt D, Warrit K et al. (2021) Effect of two different pre-anaesthetic omeprazole protocols on gastroesophageal reflux incidence and pH in dogs.Journal of Small Animal Practice 62, 677–682
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  12. Marks SL, Kook PH, Papich MG et al.(2018) ACVIM consensus statement: support for rational administration of gastrointestinal protectants to dogs and cats.  Journal of Veterinary Internal Medicine  32, 1823–1840
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  13. McCormack R, Olley L, Glanemann B and Swann JW (2020) Prospective observational study of the use of omeprazole and maropitant citrate in veterinary specialist care.Scientific Reports 10, 15727
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  14. Panti A, Bennett RC, Corletto F et al.(2009) The effect of omeprazole on oesophageal pH in dogs during anaesthesia . Journal of Small Animal Practice 50, 540–544. Erratum in:Journal of Small Animal Practice 50, 678
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  15. Parente NL, Bari Olivier N, Refsal KR and Johnson CA (2014) Serum concentrations of gastrin after famotidine and omeprazole administration to dogs.  Journal of Veterinary Internal Medicine  28, 1465–1470
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  16. Seo DH, Lee JB, Hwang JH et al.(2019) Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs. Journal of Veterinary Internal Medicine  33, 531–535
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  17. Spencer A, Quimby JM, Price JM et al. (2021) Appetite-stimulating effects of once-daily omeprazole in cats with chronic kidney disease: Double-blind, placebo-controlled, randomized, crossover trial. Journal of Veterinary Internal Medicine 35, 2705–2712
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  18. Šutalo S, Ruetten M, Hartnack S et al. (2015) The effect of orally administered ranitidine and once-daily or twice-daily orally administered omeprazole on intragastric pH in cats.  Journal of Veterinary Internal Medicine  29, 840–846
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  19. Tolbert K ,Bissett S ,King A et al. (2011)Efficacy of oral famotidine and 2 omeprazole formulations for the control of intragastric pH in dogs. Journal of Veterinary Internal Medicine 25 ,47–54
  20. Williamson KK, Willard MD, Payton ME and Davis MS (2010) Efficacy of omeprazole versus high-dose famotidine for prevention of exercise-induced gastritis in racing Alaskan sled dogs. Journal of Veterinary Internal Medicine  24, 285–288
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