1887

Phenobarbital (Phenobarbitone)

This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition
  1. Charalambous M, Brodbelt D and Volk HA (2014) Treatment in canine epilepsy – a systematic review. BMC Veterinary Research 10, 257
  2. Finnerty KE ,Barnes Heller HL ,Mercier MN et al.(2014)Evaluation of therapeutic phenobarbital concentrations and application of a classification system for seizures in cats: 30 cases (2004–2013). Journal of the American Veterinary Medical Association 244 ,195199
  3. Bateman SW andParent JM (1999)Clinical findings, treatment, and outcome of dogs with status epilepticus or cluster seizures: 156 cases (1990–1995). Journal of the American Veterinary Medical Association 215 ,14631468
  4. Bersan E, Volk HA, Ros C and De Risio L (2014) Phenobarbitone-induced haematological abnormalities in idiopathic epileptic dogs: prevalence, risk factors, clinical presentation and outcome.Veterinary Record 175, 247
  5. Bunch SE (1993) Hepatotoxicity associated with pharmacologic agents in dogs and cats.Veterinary Clinics of North America: Small Animal Practice 23, 659–670
  6. Charalambous M, Pakozdy A, Bhatti SFM and Volk HA (2018) Systematic review of antiepileptic drugs' safety and effectiveness in feline epilepsy. BMC Veterinary Research 14, 64 
  7. Farnbach GC (1984) Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy.Journal of the American Veterinary Medical Association 184, 1117–1120
  8. Muñana KR1, Nettifee-Osborne JA and Papich MG (2015) Effect of chronic administration of phenobarbital, or bromide, on pharmacokinetics of levetiracetam in dogs with epilepsy.Journal of Veterinary Internal Medicine 29, 614–619
  9. Marsh O, Corsini G, Van Dijk J, Gutierrez-Quintana R and De Risio L (2021) Prevalence and clinical characteristics of phenobarbitone-associated adverse effects in epileptic cats.Journal of Feline Medicine and Surgery 23, 59–66
  10. Walker R, Fisher J and Neville P (1997) The treatment of phobias in the dog. Applied Animal Behaviour Science 52, 275–289
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