Topiramate
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This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition.
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Caldwell GW, Wu WN, Masucci JA et al. (2005) Metabolism and excretion of the antiepileptic/antimigrane drug, topiramate in animals and humans. European Journal of Drug Metabolism and Pharmacokinetics 30, 151–164
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Centola SJ, Kaiman G, Rizzo K et al. (2022) Presumptive renal tubular acidosis secondary to topiramate administration in a cat. Journal of Veterinary Emergency and Critical Care (San Antonio) 32,420–425
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Graham LT, Foss KD, Reinhart JM et al. (2023) The pharmacokinetics of single oral dose extended-release topiramate and adverse effects after multi-dose administration in healthy cats. Journal of Veterinary Pharmacology and Therapeutics 46, 218–228
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Grant D and Rusbridge C (2014) Topiramate in the management of feline idiopathic ulcerative dermatitis in a two-year-old cat. Veterinary Dermatology 25, 226–228
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Hunt S, Russel A, Smithson WH et al (2008) Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. Neurology 71, 272–276
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Kiviranta AM, Laitinen-Vapaavuori O, Hielm-Björkman A et al. (2013) Topiramate as an add-on antiepileptic drug in treating refractory canine idiopathic epilepsy. Journal of Small Animal Practice 54, 512–520
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Mula M, Cavanna AE, Monaco F (2006) Pharmacology of topiramate: from epilepsy to bipolar disorder. Neuropsychiatric Disease and Treatment 2, 475–488
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Plessas IN, Volk HA and Kenny PJ (2013) Migraine-like episodic pain behavior in a dog: can dogs suffer from migraines? Journal of Veterinary Internal Medicine 27, 1034–1040
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Plessas IN, Volk HA, Rusbridge C et al. (2015) Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia. Veterinary Record 177, 288
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Rusbridge C (2024) Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery 26, 1098612X241246518
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Streeter AJ, Stahle PL, Holland ML et al. (1995) Pharmacokinetics and bioavailability of topiramate in the beagle dog. Drug metabolism and disposition: the biological fate of chemicals 23, 90–93
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Tomson T, Battino D, Bonizzoni E et al. (2018) Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. The Lancet Neurology 17, 530–538
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Vuu I, Coles LD, Maglalang P et al. (2016) Intravenous Topiramate: pharmakokinetics in dogs with naturally occurring epilepsy. Frontiers in Veterinary Science 3, 107