1887

Topiramate

This is a drug monograph from the BSAVA Small Animal Formulary Part A: Canine and Feline. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition
  1. Batle PA, Rusbridge C, Nuttal T et al. (2019) Feline hyperaesthesia syndrome with self-trauma to the tail: retrospective study of seven cases and proposal for an integrated multidisciplinary diagnostic appraoch. Journal of Feline Medicine and Surgery 21, 178–185
  2. Caldwell GW, Wu WN, Masucci JA et al. (2005) Metabolism and excretion of the antiepileptic/antimigrane drug, topiramate in animals and humans. European Journal of Drug Metabolism and Pharmacokinetics 30, 151–164
  3. Centola SJ, Kaiman G, Rizzo K et al. (2022) Presumptive renal tubular acidosis secondary to topiramate administration in a cat. Journal of Veterinary Emergency and Critical Care (San Antonio) 32,420–425
  4. Graham LT, Foss KD, Reinhart JM et al. (2023) The pharmacokinetics of single oral dose extended-release topiramate and adverse effects after multi-dose administration in healthy cats. Journal of Veterinary Pharmacology and Therapeutics 46, 218–228
  5. Grant D and Rusbridge C (2014) Topiramate in the management of feline idiopathic ulcerative dermatitis in a two-year-old cat. Veterinary Dermatology 25, 226–228
  6. Hunt S, Russel A, Smithson WH et al (2008) Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. Neurology 71, 272–276
  7. Kiviranta AM, Laitinen-Vapaavuori O, Hielm-Björkman A et al. (2013) Topiramate as an add-on antiepileptic drug in treating refractory canine idiopathic epilepsy. Journal of Small Animal Practice 54, 512–520
  8. Mula M, Cavanna AE, Monaco F (2006) Pharmacology of topiramate: from epilepsy to bipolar disorder. Neuropsychiatric Disease and Treatment 2, 475–488
  9. Plessas IN, Volk HA and Kenny PJ (2013) Migraine-like episodic pain behavior in a dog: can dogs suffer from migraines? Journal of Veterinary Internal Medicine 27, 1034–1040
  10. Plessas IN, Volk HA, Rusbridge C et al. (2015) Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia. Veterinary Record 177, 288
  11. Rusbridge C (2024) Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery 26, 1098612X241246518
  12. Streeter AJ, Stahle PL, Holland ML et al. (1995) Pharmacokinetics and bioavailability of topiramate in the beagle dog. Drug metabolism and disposition: the biological fate of chemicals 23, 90–93
  13. Tomson T, Battino D, Bonizzoni E et al. (2018) Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. The Lancet Neurology 17, 530–538
  14. Vuu I, Coles LD, Maglalang P et al. (2016) Intravenous Topiramate: pharmakokinetics in dogs with naturally occurring epilepsy. Frontiers in Veterinary Science 3, 107
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