1887

Buprenorphine

This is a drug monograph from the BSAVA Small Animal Formulary Part B: Exotic Pets. BSAVA members should login for access to the full monograph. Non-members can join BSAVA, buy a Formulary subscription, or buy the printed edition.
  1. Cooper CS, Metcalf-Pate KA, Barat CE, Cook JA and Scorpio DG (2009) Comparison of side effects between buprenorphine and meloxicam used postoperatively in Dutch belted rabbits (Oryctolagus cuniculus). Journal of the American Association of Laboratory Animal Science 48(3), 279–285
  2. Doss GA and Mans C (2020) Antinociceptive efficacy and safety of subcutaneous buprenorphine hydrochloride administration in African pygmy hedgehogs (Atelerix albiventris). Journal of the American Veterinary Medical Association 257(6), 618–623
  3. Doss GA and Knych HK (2024) Pharmacokinetics of a single, deep subcutaneous dose of buprenorphine hydrochloride in four-toed hedgehogs (Atelerix albiventris). Journal of Exotic Pet Medicine 50, 1–4
  4. Foley PL, Kendall LV and Turner PV (2019) Clinical management of pain in rodents. Comparative Medicine 69(6), 468–489
  5. Fox L and Mans C (2018) Analgesic efficacy and safety of buprenorphine in chinchillas (Chinchilla lanigera). Journal of the American Association for Laboratory Animal Science 57(3), 286–290
  6. Guarnieri M, Brayton C, DeTolla L, Forbes-McBean N, Sarabia-Estrada R and Zadnik P (2012) Safety and efficacy of buprenorphine for analgesia in laboratory mice and rats. Lab Animal 41(11), 337–343
  7. Gades NM, Danneman PJ, Wixson SK and Tolley EA (2000) The magnitude and duration of the analgesic effect of morphine, butorphanol, and buprenorphine in rats and mice. Contemporary Topics in Laboratory Animal Science 39(2), 8–13
  8. Katzenbach JE, Wittenburg LA, Allweiler SI, Gustafson DL and Johnston MS (2018) Pharmacokinetics of single-dose buprenorphine, butorphanol, and hydromorphone in the domestic ferret (Mustela putorius furo). Journal of Exotic Pet Medicine 27(2), 95–102
  9. Kelly KR, Pypendop BH and Christe KL (2014) Pharmacokinetics of buprenorphine following intravenous and intramuscular administration in male rhesus macaques (Macaca mulatta). Journal of Veterinary Pharmacology and Therapeutics 37(5), 480–485
  10. Nunamaker EA, Halliday LC, Moody DE (2013) Pharmacokinetics of 2 formulations of buprenorphine in macaques (Macaca mulatta and Macaca fascicularis). Journal of the Association of Laboratory Animal Science 52, 48–56
  11. Sadar MJ, Knych HK, Drazenovich TL and Paul-Murphy JR (2018) Pharmacokinetics of buprenorphine after intravenous and oral transmucosal administration in guinea pigs (Cavia porcellus). American Journal of Veterinary Research 79(3) 260–266
  12. Shafford HL and Schadt JC (2008) Effect of buprenorphine on the cardiovascular and respiratory response to visceral pain in conscious rabbits. Veterinary Anaesthesia and Analgesia 35(4), 333–340
  13. Tubbs JT, Kissling GE, Travlos GS et al. (2011) Effects of buprenorphine, meloxicam, and flunixin meglumine as postoperative analgesia in mice. Journal of the American Association for Laboratory Animal Science 50(2), 185–191
  14. Aliansyah E, Chng HT and Xie S (2021) A critical review of the pharmacokinetics and pharmacodynamics of opioid medications used in avian patients. Birds 3(1), 1–28
  15. Douglas JM, Guzman DSM, Beaufrère H and Paul-Murphy JR (2025) High doses of buprenorphine hydrochloride are well tolerated and produce a mild and prolonged thermal antinociceptive effect in orange-winged Amazon parrots (Amazona amazonica). American Journal of Veterinary Research 1, 1–6
  16. Gleeson MD, Guzman DSM, Knych HK, Kass PH, Drazenovich TL and Hawkins MG (2018). Pharmacokinetics of a concentrated buprenorphine formulation in red-tailed hawks (Buteo jamaicensis). American Journal of Veterinary Research 79(1), 13–20
  17. Guzman DSM, Houck EL, Knych HKD, Beaufrère H and Paul-Murphy JR (2018) Evaluation of the thermal antinociceptive effects and pharmacokinetics after intramuscular administration of buprenorphine hydrochloride to cockatiels (Nymphicus hollandicus). American Journal of Veterinary Research 79(12), 1239–1245
  18. Guzman DSM, Ceulemans SM, Beaufrère H, Olsen GH and Paul-Murphy JR (2018) Evaluation of the thermal antinociceptive effects of a sustained-release buprenorphine formulation after intramuscular administration to American kestrels (Falco sparverius). Journal of Avian Medicine and Surgery 32(1), 1–7
  19. Paul-Murphy J, Hess JC and Fialkowski JP (2004) Pharmacokinetic properties of a single intramuscular dose of buprenorphine in African Grey Parrots (Psittacus erithacus). Journal of Avian Medicine and Surgery 18(4), 224–228
  20. Kummrow MS, Tseng F, Hesse L and Court M (2008) Pharmacokinetics of buprenorphine after single-dose subcutaneous administration in red-eared sliders (Trachemys scripta elegans). Journal of Zoo and Wildlife Medicine 39(4), 590–595
  21. Mans C, Lahner LL, Baker BB, Johnson SM and Sladky KK (2012) Antinociceptive efficacy of buprenorphine and hydromorphone in red-eared slider turtles (Trachemys scripta elegans). Journal of Zoo and Wildlife Medicine 43(3), 662–665 Greenacre CB, Takle G, Schumacher JP, Klaphake EK and Harvey RC (2006) Comparative antinociception of morphine, butorphanol, and buprenorphine versus saline in the green iguana, Iguana iguana, using electrostimulation. Journal of Herpetological Medicine and Surgery 16(3), 88–92
  22. Koeller CA (2009) Comparison of buprenorphine and butorphanol analgesia in the eastern red-spotted newt (Notophthalmus viridescens). Journal of the American Association of Laboratory Animal Science 48(2), 171–175
  23. Machin KL (1999) Amphibian pain and analgesia. Journal of Zoo and Wildlife Medicine 30, 2–10
  24. Mettam JJ, Oulton LJ, McCrohan CR and Sneddon LU (2011) The efficacy of three types of analgesic drugs in reducing pain in the rainbow trout (Oncorhynchus mykiss). Applied Animal Behaviour Science 133(3–4), 265–274
  25. Sneddon LU (2012) Clinical anaesthesia and analgesia in fish. Journal of Exotic Pet Medicine 21, 32–43
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